Role of the Drug-Metabolizing Enzyme CYP during Mouse Liver Development
نویسندگان
چکیده
منابع مشابه
Role of farnesoid X receptor in establishment of ontogeny of phase-I drug metabolizing enzyme genes in mouse liver
The expression of phase-I drug metabolizing enzymes in liver changes dramatically during postnatal liver maturation. Farnesoid X receptor (FXR) is critical for bile acid and lipid homeostasis in liver. However, the role of FXR in regulating ontogeny of phase-I drug metabolizing genes is not clear. Hence, we applied RNA-sequencing to quantify the developmental expression of phase-I genes in both...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2016
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.b16-00479